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Research Sissy Cambridge Research summary The allocation of Sissy Cambridge to a specific lineage is directed by the activities of key alling pathways and developmentally regulated transcription factors that in turn regulate gene expression. Muslim dating sites Niagara Falls free these factors can maintain the pluripotency or direct the differentiation of stem cells. We have generated inducible mouse embryonic stem mES cell lines that overexpress various transcription factors and seek to identify the molecular hierarchy involved in disruption of the pluripotency regulatory network and induction of differentiation. We aim to characterise the genetic and epigenetic mechanisms involved in pluripotency inhibition The working man Sydney ms investigate the impact of stem cell state and alling on lineage decisions. Understanding the basis of lineage restriction will further elucidate events in early embryogenesis and facilitate efforts to direct stem cell differentiation for disease modelling and therapeutic application.

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